|Application ||IHC-P, E|
|Calculated MW||44442 Da|
|Purification||Antisera to human TACR2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic Peptide corresponding to the C-Terminal of Human TACR2, conjugated to keyhole limpet hemocyanin (KLH).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Substance-K receptor, SKR, NK-2 receptor, NK-2R, Neurokinin A receptor, Tachykinin receptor 2, TACR2, NK2R, NKNAR, TAC2R|
|Target/Specificity||Rabbit anti-human TACR2 (C terminal) recognizes TACR2 (Tachykinin Receptor 2), a ~45 kDa cell membrane protein, the receptor for the tachykinin neuropeptide substance K, also known as neurokinin A. TACR2 belongs to a family of tachykinin receptors characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. TACR2 is associated with G proteins that activate a phosphatidylinositol- calcium second messenger system, it mediates smooth muscle contraction in the central airway and it has been suggested that it may linked to the development of asthma.TACR2 expression has been reported from a range of tissues including the trachea, lung, brain and the gastrointestinal tract.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human TACR2 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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