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Anti-Human CD156b Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human CD156b Antibody  ABD11023
    Staining of formalin fixed, paraffin embedded human skeletal muscle with Rabbit anti Human CD156b
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Z1K9
Other Accession P78536
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 93017 Da
Additional Information
Other Species M,Rat
Purification Antisera to human CD156b were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.
Immunogen Synthetic Peptide sequence corresponding to amino acids 807-823 of human CD156b
Shelf Life 18 months from date of despatch.
Gene ID 57027
Other Names Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17,, TNF-alpha convertase, TNF-alpha-converting enzyme, CD156b, Adam17, Tace
Target/Specificity Rabbit anti-Human CD156b antibody recognises Human CD156b, also known as ADAM17, a type I transmembrane glycoprotein which belongs to the ADAM (a disintegrin and metalloprotease domain) family.CD156b functions as a tumour necrosis factor-alpha converting enzyme (TACE). CD156b also causes a number of inflammatory modulators to undergo ectodomain shedding, including TNFR75, IL-1RII, TNFR55, L-selectin, and the amyloid precursor protein among others. CD156b plays a prominent role in the activation of the Notch signalling pathway.CD156b also plays a pivotal role in several acquired tumor cell capabilities by mediating the availability of soluble transforming growth factor-alpha, and establishing an autocrine signaling pathway through endogenous EGFR activation. CD156b is therefore a prospective therapeutic target in human cancer.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3)
Storage Store at +4℃. DO NOT FREEZE.
PrecautionsAnti-Human CD156b Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11023
(40 western blots)
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