|Application ||WB, IHC-P, E|
|Calculated MW||109685 Da|
|Purification||Antiserum to human kinesin heavy chain (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Peptide sequence C-QPVAVRGGGGKQV from the C-terminal region of kinesin heavy chain (NP_004512.).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Kinesin-1 heavy chain, Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC, KIF5B, KNS, KNS1|
|Target/Specificity||Goat anti-Human Kinesin heavy chain antibodyrecognizes the heavy chain of human kinesin, also known as Kinesin-1 heavy chain, Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain or KIF5B. Kinesin heavy chain is a 963 amino acid microtubule dependent motor containing a kinesin motor domain. otherwise known as , a member of the kinesin-like protein family and principal component of kinesin, involved in the plus end-directed transport of eukaryotic cell vesicles and organelles. Goat anti-human kinesin heavy chain antibody binds to an epitope within the C-terminal (CT) region of human kinesin heavy chain (KHC), Kinesins are microtubule associated motor proteins which consist of 2 identical (60-70kDa) light chains and 2 identical (110-120kDa) heavy chains, the latter of which contain a globular C-terminal tail domain, a central alpha helical rod domain and a globular N-terminal motor domain with microtubule-stimulated ATPase activity.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Kinesin Heavy Chain (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Navone, F. et al. (1992) Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells.J. Cell Biol. 117: 1263-1275.
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