|Application ||WB, IHC-P, IF, E|
|Calculated MW||55103 Da|
|Purification||Antiserum to human HDAC1 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to amino acid sequence 666-482 of Human HDAC-1.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Histone deacetylase 1, HD1, 188.8.131.52, HDAC1, RPD3L1|
|Target/Specificity||Rabbit anti-Human Histone deacetylase recognizes human histone deacetylase 1 (HDAC1), also known as RPD3L1. HDAC1 is a 482 amino acid member of the histone deacetylase family responsible for the deacetylation of core histone N-terminal lysines. Histone acetylation and deacetylation play important roles in modifying chromatin structure and regulating eukaryotic gene expression. HDAC1 is a ubiquitously expressed ~62kD class I HDAC enzyme which is related to the yeast transcriptional regulator Rpd3p (Bertoset al.2001).|
|Preservative & Stabilisers||0.01% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Histone Deacetylase 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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