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Anti-STIM2 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-STIM2 Antibody  ABD11039
    Western blot analysis of whole cell lysate from A20 mouse B-cell lymphoma cells probed with Rabbit anti Human STIM2 at 0.5(A), 1(B) and 2(C) ug/ml
  • IHC-P - Anti-STIM2 Antibody  ABD11039
    Formalin fixed, paraffin embedded human spleen stained with Rabbit anti Human STIM2 following heat mediated antigen retrieval using sodium citrate buffer (pH6.0)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P246
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 83971 Da
Additional Information
Other Species M,Rat
Purification Antisera to human STIM2 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen A 17 amino acid peptide located near the centre of human STIM2.
Shelf Life 18 months from date of despatch.
Gene ID 57620
Other Names Stromal interaction molecule 2, STIM2, KIAA1482
Target/Specificity ABD11039 recognises an internal region of stromal interaction molecule-2 (STIM2), a ubiquitously expressed type I membrane protein, of which at least three isoforms have been identified. In T-lymphocytes and other haematopoietic cells, the mechanism for increasing intracellular Ca2+, following antigen mediated T-cell activation, is through the store-operated Ca2+release-activated Ca2+ (CRAC) channels. STIM1 is reported to activate CRAC channels upon Ca2+depletion. Whereas, STIM2 acts to inhibit the STIM1-mediated store-operated Ca2+entry, and forms complexes with STIM1, suggesting that these molecules may play a co-ordinated role in controlling Ca2+entry.
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-STIM2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11039
(40 western blots)
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
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