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Anti-SMAD3 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-SMAD3 Antibody  ABD11048
    Staining of formalin fixed, paraffin embedded human skin with Rabbit anti Mouse SMAD3
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P84022
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 48081 Da
Additional Information
Other Species M,Pig,Rat,Amphibia,Zf,B,C
Purification Antiserum to human SMAD3 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen Synthetic peptide corresponding to amino acids 417-425 of human SMAD3 protein.
Shelf Life 18 months from date of despatch.
Gene ID 4088
Other Names Mothers against decapentaplegic homolog 3, MAD homolog 3, Mad3, Mothers against DPP homolog 3, hMAD-3, JV15-2, SMAD family member 3, SMAD 3, Smad3, hSMAD3, SMAD3, MADH3
Target/Specificity ABD11048 recognises Mothers against decapentaplegic homolog 3 (SMAD3), a 50kDa transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase, SMAD3 functions in cell proliferation, differentiation and development. Upon stimulation, SMAD3 oligomerizes with SMAD4 and translocates into the nucleus where it binds to DNA and transcription factors. SMAD3 activity induces differentiation of selected neuronal subtypes at the expense of other subtypes. Studies have indicated that defects in SMAD3 may be a cause of colorectal cancer.
Preservative & Stabilisers 0.01% Sodium Azide (NaN3)
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-SMAD3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11048
(40 western blots)
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
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