|Application ||WB, IP|
|Calculated MW||153892 Da|
|Purification||Antiserum to human Rad50 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to an epitope within amino acid residues 50-100 of human Rad50 (NP_005723.2).|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||DNA repair protein RAD50, hRAD50, 3.6.-.-, RAD50|
|Target/Specificity||Rabbit anti-human Rad50 antibody specifically recognizes the coiled-coil protein Rad50, a component of the Mre11/Rad50/Nbs1 (MRN) complex and distantly related member of the SMC protein family, involved in DNA double-strand break repair, DNA recombination, cell cycle checkpoint activation, telomere integrity and meiosis.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃. DO NOT FREEZE.|
|Precautions||Anti-Human RAD50 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Williams, R.S. et al. (2007) Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template. Biochem. Cell Biol. 85: 509-520.
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