|Calculated MW||54294 Da|
|Purification||Antisera to DOPA Decarboxylase receptor were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||SDS denatured, recombinant bovine DOPA decarboxylase expressed E. coli and purified from inclusion bodies.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Aromatic-L-amino-acid decarboxylase, AADC, 188.8.131.52, DOPA decarboxylase, DDC, DDC|
|Target/Specificity||ABD11072 recognises DOPA decarboxylase (aromatic-L-amino acid decarboxylase, DDC), an enzyme that catalyses the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. The enzyme is expressed ubiquitously and is essential for the formation of catecholamines, indoleamines and trace amines. DDC is considered to be the rate-limiting step for the formation of trace amines, but not for the formation of catecholamines or indoleamines. It also becomes rate-limiting for dopamine formation in Parkinson’s disease patients treated with L-DOPA.|
|Preservative & Stabilisers||0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Bovine DOPA Decarboxylase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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