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Anti-Human LRP6 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human LRP6 Antibody  ABD11075
    Staining of formalin fixed, paraffin embedded human liver with Rabbit anti Human LRP6
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75581
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 180429 Da
Additional Information
Purification Antisera to human LRP6 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.
Immunogen A synthetic peptide corresponding to amino acids 1546 - 1560 of human LRP6 – conjugated to KLH
Shelf Life 18 months from date of despatch.
Gene ID 4040
Other Names Low-density lipoprotein receptor-related protein 6, LRP-6, LRP6
Target/Specificity ABD11075 recognises human Low density lipoprotein receptor related-protein 6 (LRP6), a 180.4 kDa single pass type 1 membrane protein belonging to the LDLR family. LRP6 is an essential component of the Wnt/beta catenin signalling pathway where it is believed to act as a co-receptor with Frizzled for Wnt. It is a specific high affinity receptor for DKK1 and DKK2. LRP6 is implicated in a wide range of normal and disease processes connected with lipid metabolism. It is co-expressed with LDR5 during embryogenesis and in adult tissues. Defects in LRP6 cause autosomal dominant coronary artery disease type 2.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human LRP6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11075
(40 western blots)
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