|Application ||WB, E|
|Calculated MW||33520 Da|
|Purification||Antiserum to human CDX2 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Peptide sequence EQLSPGGQRRNLCE corresponding to the internal region of CDX2 (NP_001256.1).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Homeobox protein CDX-2, CDX-3, Caudal-type homeobox protein 2, CDX2, CDX3|
|Target/Specificity||ABD11077 specifically recognises human CDX2 (caudal-type homeobox protein 2), a nuclear protein and member of the caudal homeobox family, which acts as a regulator for intestinal epithelium gene transcription, and possibly for the differentiation and proliferation of intestinal epithelial cells.Studies have revealed the expression of CDX2 in intestinal-type gastric cancer, colorectal carcinomas and intestinal metaplasia of the stomach, and have implicated CDX2 as an early marker of Barrett's oesophagus, the premalignant lesion of oesophageal adenocarcinoma (EAC).ABD11077 is not expected to recognise CDX1 or CDX4.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CDX2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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