|Application ||WB, IF, IP|
|Calculated MW||47535 Da|
|Purification||Antiserum to human CtBP1 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Recombinant human CtBP1 expressed in bacteria.|
|Shelf Life||18 months from date of despatch.|
|Other Names||C-terminal-binding protein 1, CtBP1, 1.1.1.-, CTBP1, CTBP|
|Target/Specificity||ABD11085 specifically recognises CtBP1 (C-terminal binding protein 1), a 49kDa highly conserved phosphoprotein, originally identified through interaction with the C-terminal portion of adenovirus E1A protein, which primarily acts as a transcriptional corepressor and regulator of target gene transcription, throughout development and malignant transformation.ABD11085 is suitable for use in immunofluorescence studies on cells using acetone/methanol fixation.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-CTBP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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1. Valenta, T. et al. (2006) HIC1 attenuates Wnt signaling by recruitment of TCF-4 and Beta-catenin to the nuclear bodies. EMBO J. 25: 2326-2337.
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