|Application ||WB, IF|
|Calculated MW||51113 Da|
|Purification||Antisera to human TGN46 were raised by repeated immunisation of rabbits with highly purified recombinant human TGN46.|
|Immunogen||Recombinant human TGN46.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Trans-Golgi network integral membrane protein 2, TGN38 homolog, TGN46, TGN48, Trans-Golgi network protein TGN51, TGOLN2, TGN46, TGN51|
|Target/Specificity||Rabbit anti-Human TGN46 antibody recognizes Trans-Golgi network integral membrane protein 2, also known as TGN46, TGN38 homolog or Trans-Golgi network protein TGN51. TGN46 is a 480 amino acid ~110kDa single pass type I transmembrane glycoprotein associated with the trans golgi network membrane. TGN46 has been reported as being the best available marker for human trans-Golgi network.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3); 1% Bovine Serum Albumin; 50% Glycerol|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human TGN46 Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Prescott, A.R. et al. (1997) Distinct compartmentalization of TGN46 and beta 1, 4-galactosyltransferase in Hela cells.Eur. J. Cell Biol. 72: 238-246. 2. Ponnambalam, S. et al. (1996) Primate homologues of rat TGN38: primary structure, expression and functional implications.J. Cell Sci. 109: 675-685. 3. Vuillier, F. et al. (2005) Lower levels of surface B-cell-receptor expression in chronic lymphocytic leukemia are associated with glycosylation and folding defects of the mu and CD79a chains.Blood. 105: 2933-2940. 4. Cerqueira, C. et al. (2015) Kallikrein-8 proteolytically processes Human papillomaviruses in the extracellular space to facilitate entry into host cells.J Virol. pii: JVI.00234-15.
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