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Anti-RIP2 (N-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • ICC - Anti-RIP2 (N-Terminal) Antibody  ABD11090
    Immunocytochemical staining of A431 cells with Rabbit anti RIP-2
  • WB - Anti-RIP2 (N-Terminal) Antibody  ABD11090
    Western blot analysis of whole cell lysates from A431 (A) and K562 (K) cells probed with Rabbit anti RIP-2
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43353
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 61195 Da
Additional Information
Other Species Rat,M
Purification Antiserum to human RIP2 (NT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen A peptide corresponding to amino acids near the amino terminus of human RIP2.
Shelf Life 18 months from date of despatch.
Gene ID 8767
Other Names Receptor-interacting serine/threonine-protein kinase 2,, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, CARD-containing IL-1 beta ICE-kinase, RIP-like-interacting CLARP kinase, Receptor-interacting protein 2, RIP-2, Tyrosine-protein kinase RIPK2,, RIPK2, CARDIAK, RICK, RIP2
Target/Specificity Rabbit anti-Human RIP2 antibody recognizes Human Receptor-interacting serine/threonine-protein kinase 2, also known as RIP2, RIPK2, RIP-like-interacting CLARP kinase or CARD-containing interleukin-1 beta-converting enzyme-associated kinase. RIP2 is a 403 amino acid ~60 kDa cytoplasmic protein belonging to the protein kinase superfamily. RIP2 is a kinase that regulates TNF and Fas induced-apoptosis and is involved in the generation of the pro-inflammatory cytokine IL-1beta. Over expression of RIP2 has been shown to induce apoptosis, and the activation of NF-Kappa-B and JNK. RIP2 is widely expressed in a range of human tissues.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-RIP2 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Inohara N., et al (1998) RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis.
J Biol Chem. 273:12296-300.2. McCarthy J.V., et al (1998) RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase.
J Biol Chem. 273:16968-75.3. Thome M., et al (1998) Identification of CARDIAK, a RIP-like kinase that associates with caspase-1.
Curr Biol. 8:885-8.

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Cat# ABD11090
(40 western blots)
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