|Application ||WB, IF|
|Purification||Antisera to TGN38 were raised by repeated immunisations of rabbits with highly purified antigen.|
|Immunogen||Recombinant protein corresponding to extracellular domain of TGN38.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Trans-Golgi network integral membrane protein TGN38, Ttgn1|
|Target/Specificity||Rabbit anti-Rat TGN38 antibody recognizes a glycoprotein designated TGN38 that is found primarily in the Trans-golgi network, and has been found to be an excellent marker for this cellular organelle.TGN38 is likely to have a role in intracellular transport. It is the homologue of human TGN46.|
|Preservative & Stabilisers||0.09% Sodium Azide, ; 1% Bovine Serum Albumin;|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Rat TGN38 Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Ponnambalam, S. et al. (1996) Primate homologues of rat TGN38: primary structure, expression and functional implications.J Cell Sci. 109 ( Pt 3): 675-85. 2. Luzio, J.P. et al. (1990) Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38).Biochem J. 270 (1): 97-102. 3. Banerji, S. et al. (2010) Oxysterol binding protein-dependent activation of sphingomyelin synthesis in the golgi apparatus requires phosphatidylinositol 4-kinase IIα.Mol Biol Cell. 21 (23): 4141-50. 4. Park, B.C. et al. (2015) The clathrin-binding and J-domains of GAK support the uncoating and chaperoning of clathrin by Hsc70 in the brain.J Cell Sci. pii: jcs.171058. 5. Chen, A. et al. (2012) Regional and subcellular distribution of the receptor-targeting protein PIST in the rat central nervous system.J Comp Neurol. 520 (5): 889-913.
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