|Application ||WB, IHC-P|
|Calculated MW||32680 Da|
|Purification||Antiserum to human DcR3 (NT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography.|
|Immunogen||A peptide corresponding to amino acids near the amino-terminus of human DcR3 precursor.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tumor necrosis factor receptor superfamily member 6B, Decoy receptor 3, DcR3, Decoy receptor for Fas ligand, M68, TNFRSF6B, DCR3, TR6|
|Target/Specificity||Rabbit anti-Human DcR3 (N-Terminal) antibody recognizes the amino Terminal of human DcR3, otherwise known as Decoy Receptor 3, a 33kDa member of the tumour necrosis factor receptor superfamily. DcR3 acts as a receptor for FasL and LIGHT, preventing them from binding to their cell death receptors and thereby inhibiting apoptosis. DcR3 is a soluble decoy receptor found in adult stomach, spinal cord, lymph node, trachea, spleen and lung. It may also be found in fetal lung, brain and liver and is highly expressed in several primary tumours from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human DcR3 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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