|Application ||WB, IHC-F|
|Calculated MW||150254 Da|
|Purification||Antiserum to human IKBKAP was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||A peptide corresponding to 16 amino acids from near the carboxy terminus of human IKBKAP .|
|Shelf Life||18 months from date of despatch.|
|Other Names||Elongator complex protein 1, ELP1, IkappaB kinase complex-associated protein, IKK complex-associated protein, p150, IKBKAP, ELP1, IKAP|
|Target/Specificity||Rabbit anti-Human IKBKAP antibody recognizes human IKBKAP. IKBKAP was originally described as a scaffold protein of the IKK complex involved in NF-kB activation, but this role has since been disputed.IKBKAP is a component of the RNA polymerase II elongator complex which has histone acetyltransferase activity and is involved in transcriptional elongation. Gene defects are a cause of familial dysautonomia, also known as Riley-Day syndrome. Affected individuals show a variety of symptoms such as decreased sensitivity to pain and temperature, cardiovascular instability, pneumonia and gastrointestinal dysfunction.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human IKBKAP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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