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Anti-Human IRAK3 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • ICC - Anti-Human IRAK3 Antibody  ABD11100
    Immunocytochemical staining of rat liver with Rabbit anti Human IRAK3
  • WB - Anti-Human IRAK3 Antibody  ABD11100
    Western blot analysis of lysates from mouse spleen (M) and rat liver (R) probed with Rabbit anti Human IRAK3
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y616
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 67767 Da
Additional Information
Other Species M,Rat
Purification Antisera to human IRAK3 were raised by repeated immunisation of rabbits with highly purified antigen.
Immunogen Peptide corresponding to amino acids from the carboxy terminus of human IRAK3.
Shelf Life 18 months from date of despatch.
Gene ID 11213
Other Names Interleukin-1 receptor-associated kinase 3, IRAK-3,, IL-1 receptor-associated kinase M, IRAK-M, IRAK3 {ECO:0000312|EMBL:AAH57800.1}
Target/Specificity Rabbit anti-Human IRAK3 antibody recognizes human Interleukin-1 receptor-associated kinase 3 (IRAK3), a member of the IRAK/Pelle family. IRAKs associate with the IL1/Toll receptors after IL-1 or LPS stimulation, thereby playing an important role in the inflammatory response.IRAK3 inhibits the dissociation of IRAK1 and IRAK4 from the Toll-like receptor signalling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilising the receptor complex. It is predominantly expressed in peripheral blood lymphocytes. Defects in the IRAK3 gene are associated with susceptibility to asthma-related traits type 5.Rabbit anti-Human IRAK3 antibody does not cross-react with IRAK or IRAK2.
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human IRAK3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11100
(40 western blots)
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