Anti-Lysine-Specific Histone Demethylase (N-Terminal) Antibody
Rabbit Anti-Human Polyclonal Antibody
|Calculated MW||92903 Da|
|Purification||Antiserum to human Lysine-specific histone demethylase (N-Terminal) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||A peptide corresponding to an 17 amino acid sequence from near the amino terminus of human Lysine-specific histone demethylase.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Lysine-specific histone demethylase 1A, 1.-.-.-, BRAF35-HDAC complex protein BHC110, Flavin-containing amine oxidase domain-containing protein 2, KDM1A, AOF2, KDM1, KIAA0601, LSD1|
|Target/Specificity||Rabbit anti-Lysine-Specific Histone Demethylase (N-Terminal) antibody recognizes Lysine-specific histone demethylase (LSD1), a ubiquitously expressed nuclear protein belonging to the flavin monoamine oxidase family.Histone modifications mediate changes in gene expression by altering chromatin structure or by serving as a platform to recruit other proteins. LSD1 is an amine oxidase that catalyzes the lysine-specific demethylation of histone proteins via an FAD-dependent oxidative reaction. Methylation on histone H3-K9 is thought to play an important role in heterochromatin formation, while methylation on arginine and some lysine residues, e.g H3-K4, are associated with active transcription.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Lysine-Specific Histone Demethylase (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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