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Anti-DRAM (C-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-DRAM (C-Terminal) Antibody  ABD11113
    Immunohistochemical staining of human liver with Rabbit anti Human DRAM
  • WB - Anti-DRAM (C-Terminal) Antibody  ABD11113
    Western blot analysis of whole cell lysate from HEK293 human epithelial kidney cells probed with Rabbit anti Human DRAM at 0.5(A) and 1(B) ug/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8N682
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 26253 Da
Additional Information
Other Species M,Rat
Purification Antisera to human DRAM were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.
Immunogen A peptide corresponding to a 16 amino acid sequence from near the carboxy terminus of Human DRAM.
Shelf Life 18 months from date of despatch.
Gene ID 55332
Other Names DNA damage-regulated autophagy modulator protein 1, Damage-regulated autophagy modulator, DRAM1, DRAM
Target/Specificity Rabbit anti-DRAM (C-terminal) antibody recognizes human DRAM, a lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. DRAM is significantly down-regulated in tumor cell lines by methylation-dependent transcriptional silencing.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-DRAM (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Crighton D, et al. (2007) DRAM links autophagy to p53 and programmed cell death.
Autophagy 3:72-42. Crighton D, et al (2006) DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.
Cell 126:121-34. 3. Gozuacik D., et al (2004) Autophagy as a cell death and tumor suppressor mechanism. .
Oncogene 23:2891-906

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Cat# ABD11113
(40 western blots)
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