|Application ||WB, IHC-P|
|Calculated MW||26253 Da|
|Purification||Antisera to human DRAM were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.|
|Immunogen||A peptide corresponding to a 16 amino acid sequence from near the carboxy terminus of Human DRAM.|
|Shelf Life||18 months from date of despatch.|
|Other Names||DNA damage-regulated autophagy modulator protein 1, Damage-regulated autophagy modulator, DRAM1, DRAM|
|Target/Specificity||Rabbit anti-DRAM (C-terminal) antibody recognizes human DRAM, a lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. DRAM is significantly down-regulated in tumor cell lines by methylation-dependent transcriptional silencing.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-DRAM (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
1. Crighton D, et al. (2007) DRAM links autophagy to p53 and programmed cell death. Autophagy 3:72-42. Crighton D, et al (2006) DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 126:121-34. 3. Gozuacik D., et al (2004) Autophagy as a cell death and tumor suppressor mechanism. . Oncogene 23:2891-906
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.