|Application ||WB, IHC-P|
|Calculated MW||23363 Da|
|Purification||Antiserum to human ARMER (CT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography.|
|Immunogen||A peptide corresponding to 15 amino acids near the carboxy terminus of human ARMER.|
|Shelf Life||18 months from date of despatch.|
|Other Names||ADP-ribosylation factor-like protein 6-interacting protein 1, ARL-6-interacting protein 1, Aip-1, ARL6IP1, ARL6IP, KIAA0069|
|Target/Specificity||Rabbit anti-ARMER (C-Terminal) antibody recognizes the carboxy Terminal of ARMER (also known as ADP-ribosylation factor-like protein 6-interacting protein 1), an integral ER-membrane protein involved in protein transport, membrane trafficking and cell signalling. ARMER has been shown to protect cells against ER stress-induced apoptosis, possibly by blocking caspase-9 activity. It is expressed in all haematopoietic cell lineages with highest expression in early myeloid progenitor cells. It is expressed in brain, bone marrow, thymus and lung with lower levels in liver, kidney and spleen. It is not detected in heart.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-ARMER (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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