Anti-Human PI-3 Kinase p110 Subunit delta (C-Terminal) Antibody
Rabbit Anti-Human Polyclonal Antibody
|Application ||WB, E|
|Calculated MW||119479 Da|
|Purification||Antiserum to p110 delta (CT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide SWKTKVNWLAHNVSKDNRQ with added cysteine, corresponding to amino acids 1026-1044 within the C-terminal region of human PI3-Kinase p110 subunit delta.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Phosphatidylinositol 4, 5-bisphosphate 3-kinase catalytic subunit delta isoform, PI3-kinase subunit delta, PI3K-delta, PI3Kdelta, PtdIns-3-kinase subunit delta, 220.127.116.11, Phosphatidylinositol 4, 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, PtdIns-3-kinase subunit p110-delta, p110delta, PIK3CD|
|Target/Specificity||Rabbit anti-Human PI-3 kinase subunit Delta recognizes an epitope within the C-terminal (CT) region of human PI3-kinase p110 subunit delta (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta), a member of the PI3/PI4-kinase family of lipid kinases, implicated in the regulation of signal transduction during cell growth.PI3-kinase is a heterodimer consisting of a p85 regulatory subunit and a p110 catalytic subunit, which itself is divided into isoforms p110alpha, p110beta, p110delta and p110gamma. Studies have shown that p110delta is predominantly restricted to leucocytes, exhibits a broad phosphoinositide lipid substrate specificity, and binds to Ras-GTP and p85.Rabbit anti-Human PI-3 kinase subunit Delta is reported as suitable for use in immunocytochemistry.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 0.1% Bovine Serum Albumin;|
|Storage||Store at -20℃ only.|
|Precautions||Anti-Human PI-3 Kinase p110 Subunit delta (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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