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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human CD262 Antibody    

Anti-Human CD262 Antibody

Goat Anti-Human Polyclonal Antibody

  • IHC - Anti-Human CD262 Antibody  ABD11147
    Paraffin embedded human spleen stained with Goat anti human CD262
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9QZM4
Other Accession O14763
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 42165 Da
Additional Information
Other Species M
Purification Antiserum to human CD262 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide APQQKRSSPSEGLCPPGHHISEDGRDC corresponding to amino acids 68-94 of the extracellular domain of human CD262.
Shelf Life 18 months from date of despatch.
Gene ID 21933
Other Names Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, MK, CD262, Tnfrsf10b, Dr5, Killer
Target/Specificity Goat anti-Human CD262 antibody recognizes CD262, otherwise known as DR5/TRAIL-R2, a broadly expressed death domain containing receptor and member of the TNF-receptor superfamily, which acts as a mediator for CD253/TRAIL induced apoptosis in a variety of tumor and transformed cells, but not in normal cells. Expression of CD262 is regulated by tumor suppressor p53, and CD262 is highly expressed by tumour cell lines. Studies suggest that the death domain containing adaptor protein FADD, is required for CD262-mediated apoptosis, and that FADD recruits caspase-8 to the activated receptor.Goat anti-Human CD262 antibody is suitable for use in immunocytochemistry.
Preservative & Stabilisers 0.1% Sodium Azide (NaN3)
Storage Store at -20℃ only.
PrecautionsAnti-Human CD262 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11147
(40 western blots)
Availability: Inquire
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