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Anti-Human CD195 (N-Terminal) Antibody

Goat Anti-Human Polyclonal Antibody

  • IHC - Anti-Human CD195 (N-Terminal) Antibody  ABD11148
    Immunohistochemical staining of formalin fixed, paraffin embedded human spleen probed with Goat anti Human CD195 antibody
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51681
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 40524 Da
Additional Information
Other Species Macaque
Purification Antiserum to human CD195 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide YQVSSPIYDINYYTSEPCQKINVKQIAA corresponding to amino acids 3-30 within the N-terminal region of human CD195.
Shelf Life 18 months from date of despatch.
Gene ID 1234
Other Names C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5, CHEMR13, HIV-1 fusion coreceptor, CD195, CCR5, CMKBR5
Target/Specificity Goat anti-Human CD195 antibodyrecognizeshuman CD195, also known as C-C chemokine receptor type 5, CCR5 or C-C CKR-5. CD195 is a 353 amino acid ~37 kDa multiple pass transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, preferentially expressed by a subset of memory Th1 (type 1 helper T) cells. Goat anti-human CD195 antibody binds to an epitope within the N-terminal (NT) region of CD195.CD195 acts as a high-affinity receptor for several chemotactic chemokines, including MIP-1 alpha (macrophage inflammatory protein 1 alpha), MIP-1 beta, and RANTES (regulated on activation normal T expressed and secreted protein). CD195 is also a major co-receptor for HIV-1 infection, with variations in the CD195 gene, influencing the rate of progression into AIDS (Choeet al.1996).Goat anti-human CD195 antibody is suitable for use in immunocytochemistry on human peripheral blood leucocytes.
Preservative & Stabilisers 0.1% Sodium Azide (NaN3)
Storage Store at -20℃ only.
PrecautionsAnti-Human CD195 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11148
(40 western blots)
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