|Application ||WB, IHC-P, IHC-F, E|
|Calculated MW||40524 Da|
|Purification||Antiserum to human CD195 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide YQVSSPIYDINYYTSEPCQKINVKQIAA corresponding to amino acids 3-30 within the N-terminal region of human CD195.|
|Shelf Life||18 months from date of despatch.|
|Other Names||C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5, CHEMR13, HIV-1 fusion coreceptor, CD195, CCR5, CMKBR5|
|Target/Specificity||Goat anti-Human CD195 antibodyrecognizeshuman CD195, also known as C-C chemokine receptor type 5, CCR5 or C-C CKR-5. CD195 is a 353 amino acid ~37 kDa multiple pass transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, preferentially expressed by a subset of memory Th1 (type 1 helper T) cells. Goat anti-human CD195 antibody binds to an epitope within the N-terminal (NT) region of CD195.CD195 acts as a high-affinity receptor for several chemotactic chemokines, including MIP-1 alpha (macrophage inflammatory protein 1 alpha), MIP-1 beta, and RANTES (regulated on activation normal T expressed and secreted protein). CD195 is also a major co-receptor for HIV-1 infection, with variations in the CD195 gene, influencing the rate of progression into AIDS (Choeet al.1996).Goat anti-human CD195 antibody is suitable for use in immunocytochemistry on human peripheral blood leucocytes.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at -20℃ only.|
|Precautions||Anti-Human CD195 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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