|Application ||WB, E|
|Calculated MW||76785 Da|
|Purification||Antiserum to human p63 (CT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide C-NFDMDARRNKQQRIKEEGE corresponding to amino acids 662-680 within the C-terminal region of p63.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tumor protein 63, p63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, TP63, Tumor protein p73-like, p73L, p40, p51, TP63, KET, P63, P73H, P73L, TP73L|
|Target/Specificity||Rabbit anti-p63 antibody recognizes an epitope within the C-terminal (CT) region of tumour protein p63, otherwise known as tumour protein p73-like (p73L), a widely expressed nuclear protein and homologue of tumour suppressor p53, which acts as a sequence-specific DNA binding transcriptional activator/repressor. p63, vital for the development of the prostate and selectively expressed by normal prostate basal cells, has been shown to be a promising complementary basal cell specific marker to High Molecular Weight-Cytokeratin (HMW-CK), for the differential diagnosis of benign prostatic lesions and prostatic carcinoma. Rabbit anti-p63 antibody is reported as suitable for use in immunocytochemistry.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-p63 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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