|Application ||IHC-P, E|
|Calculated MW||59130 Da|
|Purification||Antiserum to human IL-21R (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide CILEMWNLHPSTLTLTWQDQYEELKDEATS corresponding to amino acids 35-65 within the N-terminal region of human IL-21R.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interleukin-21 receptor, IL-21 receptor, IL-21R, Novel interleukin receptor, CD360, IL21R, NILR|
|Target/Specificity||Rabbit anti-Human interleukin-21 receptor antibody recognizes an epitope within the N-terminal (NT) region of human interleukin-21 receptor (IL-21R), a type I transmembrane protein and member of the type I cytokine receptor family, selectively expressed by lymphoid tissues, which acts as the receptor for IL-21.Interaction between IL-21R and IL-21 results in the activation of several downstream signalling molecules including JAK1 and STAT1, and plays an essential role in the differentiation and proliferation of B cells, T cells and natural killer (NK) cells.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3); 0.1% Bovine Serum Albumin;|
|Storage||Store at -20℃ only.|
|Precautions||Anti-Human Interleukin-21 Receptor (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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1. Coit P et al. (2015) DNA methylation analysis of the temporal artery microenvironment in giant cell arteritis.Ann Rheum Dis. pii: annrheumdis-2014-207116.
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