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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human CD284 (N-Terminal) Antibody    

Anti-Human CD284 (N-Terminal) Antibody

Goat Anti-Human Polyclonal Antibody

  • IHC - Anti-Human CD284 (N-Terminal) Antibody  ABD11159
    Paraffin embedded human tonsil stained with Goat anti human CD284
  • IHC-P - Anti-Human CD284 (N-Terminal) Antibody  ABD11159
    Paraffin embedded mouse spleen stained with Goat anti human CD284
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00206
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 95680 Da
Additional Information
Other Species M,Rat
Purification Antiserum to human CD284 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide LIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYC corresponding to amino acids 161-192 within the N-terminal region of Human CD284.
Shelf Life 18 months from date of despatch.
Gene ID 7099
Other Names Toll-like receptor 4, hToll, CD284, TLR4
Target/Specificity Goat anti-Human CD284 antibody recognizes the human Toll-like receptor 4, also known as CD284, hToll or TLR4. CD284 is an 839 amino acid ~96 kDa single pass type I transmembrane glycoprotein expressed by peripheral blood leucocytes, activated T cells, monocytes, macrophages, dendritic cells, granulocytes and endothelial cells. CD284 plays a primary role in the activation of innate immunity (UniProt: O00206).Goat anti-Human CD284 antibody recognizes an epitope within the N-terminal (NT) region of CD284, a highly conserved member of the toll-like receptor family which acts as a receptor for bacterial lipopolysaccharides (LPS) in co-operation with CD14 and MD2 (LY96), resulting in the activation of the MyD88-dependent and MyD88-independent (TRIF-dependent) signalling pathways and the production of inflammatory cytokines. LPS-activated CD284 can also induce dendritic cell maturation via TRIF-dependent signaling.Goat anti-Human CD284 antibody is reported to be suitable for use in immunocytochemistry on acetone fixed cells.
Preservative & Stabilisers 0.1% Sodium Azide (NaN3); 0.1% Bovine Serum Albumin;
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD284 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11159
(40 western blots)
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