|Application ||WB, IHC-P|
|Calculated MW||115860 Da|
|Purification||Antiserum to human CD289 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide SLKYNNLTVVPRNLPSSLEYLLLSYNRIVKL corresponding to amino acids 205-235 within the N-terminal domain of human CD289.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Toll-like receptor 9, CD289, TLR9|
|Target/Specificity||Goat anti-Human CD289 antibody recognises an epitope within the N-terminal (NT) region of CD289, otherwise known as Toll-like receptor 9 (TLR9), a type I transmembrane glycoprotein and member of the toll-like receptor family, which triggers MyD88 and TRAF6, resulting in NF-kappaB activation, cytokine secretion and the inflammatory response. CD289 acts as a receptor for unmethylated cytidine-phosphate-guanosine dinucleotides in bacterial DNA (CpG-DNA), playing a primary role in pathogen recognition and activation of innate immunity. Goat anti-Human CD289 antibody is suitable for use in immunocytochemistry on acetone fixed cells.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD289 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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