|Application ||WB, IHC-P|
|Calculated MW||42616 Da|
|Purification||Antiserum to AdipoR1 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide SSHKGSVVAQGNGAPASNREADTVE corresponding to amino acids 2-26 within the N-terminal region of AdipoR1.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Adiponectin receptor protein 1, Progestin and adipoQ receptor family member I, ADIPOR1, PAQR1, TESBP1A|
|Target/Specificity||Goat anti-ADIPOR1 antibody recognises human Adiponectin receptor protein 1, also known as ADIPOR1 or Adiponectin receptor protein 1. ADIPOR1 is a 375 amino acid ㅣ kDa multipass transmembrane protein and receptor for adiponectin (UniProt: Q96A54).Goat anti-ADIPOR1 antibody recognizes an epitope within the N-terminal (NT) region of Adiponectin Receptor protein 1 . AdipoR1 is implicated in metabolic pathways, mediating increased fatty acid oxidation and glucose uptake by adiponectin. The expression of AdipoR1 in adipose tissue is decreased in obese humans, whilst weight loss results in increased expression.ABD11161 is reported as suitable for use in immunocytochemistry of acetone fixed cells.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 0.1% Bovine Serum Albumin;|
|Storage||Store at -20℃ only.|
|Precautions||Anti-Human Adipor1 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Shen X et al. (2012) Pioglitazone prevents hyperglycemia induced decrease of AdipoR1 and AdipoR2 in coronary arteries and coronary VSMCs.Mol Cell Endocrinol. 363 (1-2): 27-35.
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