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Rabbit Anti-Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q01650 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Polyclonal IgG |
| Calculated MW | 55010 Da |
| Purification | Antiserum to human Lat1 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography. |
|---|---|
| Immunogen | Keyhole limpet haemocyanin (KLH) conjugated synthetic peptide C-RHRKPEL, representing a portion of human LAT1. |
| Shelf Life | 18 months from date of despatch. |
| Gene ID | 8140 |
| Other Names | Large neutral amino acids transporter small subunit 1, 4F2 light chain, 4F2 LC, 4F2LC, CD98 light chain, Integral membrane protein E16, L-type amino acid transporter 1, hLAT1, Solute carrier family 7 member 5, y+ system cationic amino acid transporter, SLC7A5, CD98LC, LAT1, MPE16 |
| Target/Specificity | Rabbit anti-Human LAT1 antibody specifically recognizes human LAT1 (L-type amino acid transporter 1), a heterodimeric Na+-independent amino acid transporter protein and member of the amino acid-polyamine-organocation (APC) superfamily, involved in the high-affinity transport of large neutral amino acids, in association with SLC3A2/4F2hc.LAT1 is highly expressed in the brain and is involved in the transport of L-DOPA across the blood-brain barrier, in brain neurogenesis, and acts as a mediator of L-leucine transport across the inner blood-retinal barrier. LAT1 is involved in the cell membrane transport of the thyroid hormones triiodothyronine (T3) and thyroxine (T4) in the placenta, and is the foremost transporter of tyrosine in fibroblasts. |
| Preservative & Stabilisers | Preservative Free |
| Storage | Store at -20℃ only. |
| Precautions | Anti-Human LAT1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Research Areas
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Cat# ABD11164
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