|Application ||WB, IHC-P|
|Calculated MW||17923 Da|
|Purification||Antisera to human IL-21 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.|
|Immunogen||A synthetic peptide corresponding to 15 amino acids from near the centre of human IL-21 precursor.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interleukin-21, IL-21, Za11, IL21|
|Target/Specificity||Rabbit anti-Human interleukin-21 antibody recognizes human Interleukin-21 (IL-21), also known as Za11. IL-21 is a cytokine with immunoregulatory activity. IL-21 stimulates B- and T-cell proliferation and increases the activity of NK cells and disease-specific cytotoxic T-cells. It might also inhibit dendritic cell activation and maturation during the T-cell mediated immune response.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Interleukin-21 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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1. Tripodo, C. et al. (2010) Mast Cells and Th17 Cells Contribute to the Lymphoma-Associated Pro-Inflammatory Microenvironment of Angioimmunoblastic T-Cell Lymphoma. Am J Pathol. 177: 792-802. 2. Coit P et al. (2015) DNA methylation analysis of the temporal artery microenvironment in giant cell arteritis.Ann Rheum Dis. pii: annrheumdis-2014-207116.
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