|Calculated MW||63620 Da|
|Purification||Antisera to human FZD7 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.|
|Immunogen||An 18 amino acid synthetic peptide from the carboxyl terminus of human FZD7.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Frizzled-7, Fz-7, hFz7, FzE3, FZD7|
|Target/Specificity||ABD11169 recognises human Frizzled-7 (FZD7), a multi-pass membrane protein of 574 amino acids belonging to the G-protein coupled receptor FZ/Smo family. FZD7 is a receptor for Wnt signaling proteins. FZD7 down regulates the functions of the tumor suppressor gene APC and thereby enhances beta catenin-mediated signals. FZD7 is highly expressed adult skeletal muscle and foetal kidney. High expression is observed in the foetal lung, placenta, adult heart and brain tissues. It is specifically expressed in squamous cell oesophageal carcinomas.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-FZD7 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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