|Application ||WB, E|
|Calculated MW||27899 Da|
|Purification||Antiserum to human CD137 were raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Recombinant human CD137|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137, TNFRSF9, CD137, ILA|
|Target/Specificity||Goat anti-Human CD137 antibody specifically recognizes human CD137, otherwise known as 4-1BB ligand receptor, a type I transmembrane glycoprotein and member of the tumour necrosis factor receptor superfamily, predominantly expressed by activated T cells, which acts as a receptor for 4-1BB ligand (4-1BBL).Interaction between CD137 and 4-1BBL, acts as a co-stimulatory signal for T cell activation and expansion, and is involved in the generation of cytotoxic T cells (Tc) and in the process of antigen presentation. CD137 also binds to the adaptor proteins TRAF1, 2 and 3 to act as a signal transducer of NF-kappaB activation.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Human CD137 Antibody (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures.|
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