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Anti-Rat Metabotropic Glutamate Receptor 1a Antibody

Rabbit Anti-Rat Polyclonal Antibody

  • WB - Anti-Rat Metabotropic Glutamate Receptor 1a Antibody  ABD11176
    Western blot of 10μg of HEK293 cells expressing mGluR1a and mGluR5 showing specific immunolabeling of the ~125 kDa monomer and the ~250 kDa dimer of mGluR1a
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23385
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 133236 Da
Additional Information
Purification Antisera to metabotropic glutamate receptor 1a were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Peptide corresponding to amino acids 1115-1130 from the C-terminal region of rat mGluR1a.
Shelf Life 18 months from date of despatch.
Gene ID 24414
Other Names Metabotropic glutamate receptor 1, mGluR1, Grm1, Gprc1a, Mglur1
Target/Specificity ABD11176 recognises rat metabotropic glutamate receptor 1a (mGluR1a). The metabotropic glutamate receptors have been organised into three groups. mGluR5 and mGluR1 make up group I which, when activated, stimulates phospholipase C and activates protein kinase C to hydrolyse phosphoinositide phospholipids in the cell membrane. Group I mGluRs, but not other groups, are activated by 3, 5-dihydroxyphenylglycine (DHPG).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3); 0.01% Bovine Serum Albumin; 50% Glycerol
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Rat Metabotropic Glutamate Receptor 1a Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Copani, A et al. (2000) Reducing conditions differentially affect the functionaland structural properties of group-I and -II metabotropic glutamate receptors.
Brain Res. 867: 165-172.

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Cat# ABD11176
(40 western blots)
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