|Application ||WB, IHC-F|
|Calculated MW||133236 Da|
|Purification||Antisera to metabotropic glutamate receptor 1a were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Peptide corresponding to amino acids 1115-1130 from the C-terminal region of rat mGluR1a.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Metabotropic glutamate receptor 1, mGluR1, Grm1, Gprc1a, Mglur1|
|Target/Specificity||ABD11176 recognises rat metabotropic glutamate receptor 1a (mGluR1a). The metabotropic glutamate receptors have been organised into three groups. mGluR5 and mGluR1 make up group I which, when activated, stimulates phospholipase C and activates protein kinase C to hydrolyse phosphoinositide phospholipids in the cell membrane. Group I mGluRs, but not other groups, are activated by 3, 5-dihydroxyphenylglycine (DHPG).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 0.01% Bovine Serum Albumin; 50% Glycerol|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Rat Metabotropic Glutamate Receptor 1a Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Copani, A et al. (2000) Reducing conditions differentially affect the functionaland structural properties of group-I and -II metabotropic glutamate receptors.Brain Res. 867: 165-172.
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