|Calculated MW||78564 Da|
|Purification||Antisera to Tau were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Phosphopeptide corresponding to amino acid sequence surrounding the phosphorylated serine 416 of rat Tau.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, Mapt, Mtapt, Tau|
|Target/Specificity||ABD11177 recognises the approximately 59, 65 and 68kDa isoforms of tau when phosphorylated at Ser416. Tau is a heterogeneous group of proteins that are involved in microtubule assembly. In healthy brain tissue tau is localised to the axons of neurons. Hyperphosphorylated tau is a major component of paired helical filaments in Alzheimer’s disease brain. Serine 416 is a major phosphorylation site.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 0.01% Bovine Serum Albumin; 50% Glycerol|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Rat tau (pSer416) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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