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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Amyotrophic Lateral Sclerosis (ALS)   >   Anti-Rat NMDA Receptor NR2B (N-Terminal) Antibody    

Anti-Rat NMDA Receptor NR2B (N-Terminal) Antibody

Rabbit Anti-Rat Polyclonal Antibody

  • WB - Anti-Rat NMDA Receptor NR2B (N-Terminal) Antibody  ABD11178
    Western blot of rat hippocampal lysate showing specific immunolabeling of the ~180 kDa NR2B subunit of the NDMA receptor
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q00960
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 166071 Da
Additional Information
Purification Antisera to rat NMDA receptor NR2B subunit were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Peptide from the N-terminus of the NR2B subunit of rat NMDA receptor.
Shelf Life 18 months from date of despatch.
Gene ID 24410
Other Names Glutamate receptor ionotropic, NMDA 2B, GluN2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, NR2B, Grin2b
Target/Specificity ABD11178 recognises the NR2B subunit of the NMDA (N-methyl-D-aspartate) receptor.Receptors for NMDA belong to a group of ionotropic glutamate receptors which play a key role in the mediation of glutamate neurotransmission within the mammalian central nervous system (CNS), including involvement in memory and learning processes. Several antagonists and agonists of NMDA receptors (NMDAR) have been identified. Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage-dependent Mg2+ blockade and high Ca2+permeability.The involvement of NMDAR in the CNS has become a focus area for neurodegenerative diseases such as Alzheimer’s disease and also epilepsy and ischemic neuronal cell death.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3); 0.01% Bovine Serum Albumin; 50% Glycerol
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Rat NMDA Receptor NR2B (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Chung, H.J. et al. (2004) Regulation of the NMDA receptor complex and trafficking by activity-dependent phosphorylation of the NR2B subunit PDZ ligand.
J. Neurosci. 24: 10248-10259. 2. Popke, E.J. (2003) TOXOLOGICAL HIGHLIGHT: From anticholinesterase toxicity to Alzheimer’s disease: Important interactions of cholinergic and NMDA receptor systems.
Toxological Sciences 72: 185-187.

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Cat# ABD11178
(40 western blots)
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