|Application ||WB, IHC-F|
|Calculated MW||68265 Da|
|Purification||Antiserum to human ATG16 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to an 18 aa sequence from near the centre of human ATG16.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Autophagy-related protein 16-1, APG16-like 1, ATG16L1, APG16L|
|Target/Specificity||Rabbit anti-ATG16 (Internal Region) antibody recognizes human Autophagy-related protein 16 (ATG16). ATG16 is a member of the autophagy protein family and forms a complex with the ATG5-ATG12 conjugate. This multimeric protein has been shown to be essential for autophagosome formation in both yeast and mammals and targets the ATG5-ATG12 complex to the autophagic isolation membrane during the formation of the autophagosome. Because mammalian ATG16 has seven WD-repeats in its C-Terminal domain, it has been suggested that these may form a platform for further protein-protein interactions.Multiple isoforms of ATG16 exist.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-ATG16 (Internal Region) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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