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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human PI-3 Kinase p110 Subunit alpha Antibody    

Anti-Human PI-3 Kinase p110 Subunit alpha Antibody

Goat Anti-Human Polyclonal Antibody

  • IHC - Anti-Human PI-3 Kinase p110 Subunit alpha Antibody  ABD11181
    Paraffin embedded human brain (cerebellar cortex) stained with Goat anti human p110alpha
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P42336
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 124284 Da
Additional Information
Purification Antiserum to human p110alpha was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide C-HQWLKDKNKGEIYD from the internal region of human PI3-kinase p110 subunit alpha (NP_006209.2).
Shelf Life 18 months from date of despatch.
Gene ID 5290
Other Names Phosphatidylinositol 4, 5-bisphosphate 3-kinase catalytic subunit alpha isoform, PI3-kinase subunit alpha, PI3K-alpha, PI3Kalpha, PtdIns-3-kinase subunit alpha,, Phosphatidylinositol 4, 5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha, PtdIns-3-kinase subunit p110-alpha, p110alpha, Phosphoinositide-3-kinase catalytic alpha polypeptide, Serine/threonine protein kinase PIK3CA,, PIK3CA
Target/Specificity ABD11181 specifically recognises human PI3-kinase p110 subunit alpha (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), otherwise known as PIK3CA, a member of the PI3/PI4-kinase family of lipid kinases, implicated in the regulation of signal transduction during cell growth. PI3-kinase is a heterodimer consisting of a p85 regulatory subunit and a p110 catalytic subunit, which itself is divided into isoforms p110alpha, p110beta, p110delta and p110gamma. Studies have shown that defects in p110alpha are associated with breast, colorectal and ovarian cancers.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human PI-3 Kinase p110 Subunit alpha Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11181
(40 western blots)
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