|Application ||WB, IHC-P, E|
|Calculated MW||57507 Da|
|Purification||Antisera to Human EGR1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.|
|Immunogen||A synthetic peptide sequence corresponding to amino acid 94 - 108 of human EGR1.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Early growth response protein 1, EGR-1, AT225, Nerve growth factor-induced protein A, NGFI-A, Transcription factor ETR103, Transcription factor Zif268, Zinc finger protein 225, Zinc finger protein Krox-24, EGR1, KROX24, ZNF225|
|Target/Specificity||Rabbit anti-EGR1 antibody recognizes human Early Growth Response Protein 1. EGR1 is a ~58 kDa nuclear protein belonging to the EGR family of C2H2-type zinc-finger proteins.EGR1 functions as a transcriptional regulator. The products of target genes it activates are required for differentiation and mitogenesis. Research has also demonstrated that EGR1 expression is elevated in a range of cancers including prostate cancer where EGR1 has been shown to promote the growth of tumor cells.|
|Preservative & Stabilisers||0.01% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-EGR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Abu El-Asrar, A.M. et al (2011) Expression of high-mobility groups box-1/receptor for advanced glycation end products/osteopontin/early growth response-1 pathway in proliferative vitreoretinal epiretinal membranesMol Vis. 2011 Feb 17;17:508-18.
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