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Anti-Human FOXP2 (C-Terminal) Antibody

Goat Anti-Human Polyclonal Antibody

  • WB - Anti-Human FOXP2 (C-Terminal) Antibody  ABD11197
    Human cerebellum lysate probed with Goat anti human FOXP2
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15409
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 79919 Da
Additional Information
Purification Antiserum to human FOXP2 (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Peptide with sequence C-REIEEEPLSEDLE from the C Terminus of FOXP2.
Shelf Life 18 months from date of despatch.
Gene ID 93986
Other Names Forkhead box protein P2, CAG repeat protein 44, Trinucleotide repeat-containing gene 10 protein, FOXP2, CAGH44, TNRC10
Target/Specificity Goat anti-Human FOXP2 antibody recognizes Forkhead box protein P2, also known as FOXP2, CAG repeat protein 44 or Trinucleotide repeat-containing gene 10 protein. FOXP2 is a 715 amino acid ~80 kDa nuclear transcriptional repressor with a role in brain and lung development.Mutations in the FOXP2 gene has been identified Speech-language disorder 1 (SPCH1), a disorder characterized by severe orofacial dyspraxia with speech impairment (Laiet al.2001).Multiple potential isoforms of FOXP2 generated by alternative splicing have been described. Goat anti-Human FOXP2 antibody (ABD11197) is expected to recognize the canonical isoform 1 and also isoforms 3 and 9. However the antibody is not expected other isoforms which lack the c-terminal region (UniProt : 015409).
Preservative & Stabilisers 0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human FOXP2 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Vernes, S.C. et al. (2007) High-throughput analysis of promoter occupancy reveals direct neural targets of FOXP2, a gene mutated in speech and language disorders.
Am J Hum Genet. 81 (6): 1232-50. 2. Vernes, S.C. et al. (2006) Functional genetic analysis of mutations implicated in a human speech and language disorder.
Hum Mol Genet. 15 (21): 3154-67.

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Cat# ABD11197
(40 western blots)
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