|Application ||WB, E|
|Calculated MW||39052 Da|
|Purification||Antiserum to human WNT-4 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide sequence C-SNWLYLAKLSSVGS corresponding to amino acid residues 23-36 of WNT-4 (UniProt : P56705)|
|Shelf Life||18 months from date of despatch.|
|Other Names||Protein Wnt-4, WNT4|
|Target/Specificity||Goat anti-Human WNT-4 antibody recognizes human WNT-4, a 329 amino acid ~35 kDa secreted protein, ligand for frizzled family of seven transmembrane receptors.Mutations of the WNT-4 gene are associated with 46,XX sex reversal with dysgenesis of kidneys, adrenals, and lungs (SERKAL), a condition characterized by association of female-to-male sex reversal with dysgenesis of kidneys, adrenals, and lungs (Mandelet al.2008). Additionally, mutations in the WNT-4 gene are also associated with Mullerian aplasia and hyperandrogenism (MULLAPL), a condition affecting female development (Philibertet al.2008).|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human WNT-4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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