|Application ||WB, E|
|Calculated MW||22611 Da|
|Purification||Antiserum to human TAGLN (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide sequence C-MTGYGRPRQIIS from the C-terminal region of TAGLN (NP_003177.2; NP_001001522.1).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Transgelin, 22 kDa actin-binding protein, Protein WS3-10, Smooth muscle protein 22-alpha, SM22-alpha, TAGLN, SM22, WS3-10|
|Target/Specificity||Goat anti-Human TAGLN antibody recognizes human Transgelin, also known as TAGLN, a ~22 kDa actin-binding protein, Protein WS3-10, Smooth muscle protein 22-alpha or SM22-alpha, Transgelin is a shape change sensitive, actin cross-linking/gelling protein, and member of the calponin family, which plays a role in calcium interactions and contractile properties of the cell.TAGLN is ubiquitously expressed by vascular and visceral smooth muscle, and an early marker of smooth muscle differentiation, and also overexpressed by senescent human fibroblasts. Transgelin has been identified as a novel tumor suppressor protein, which has a markedly reduced expression in colorectal cancer samples, and may serve as an important biomarker of malignancy (Zhanget al.2010).Goat anti-Human TAGLN antibody recognizes an epitope within the C-terminal (CT) region of human transgelin.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human TAGLN (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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