|Application ||WB, E|
|Calculated MW||46106 Da|
|Purification||Antiserum to human Beta arrestin-2 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide sequence C-HDHIPLPRPQS from the internal region of the ARRB2 near the C-terminus (aa 350-360) as indicated in UniProt entry: P32121.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Beta-arrestin-2, Arrestin beta-2, ARRB2, ARB2, ARR2|
|Target/Specificity||Goat anti-Human beta arrestin-2 antibody recognises human beta arrestin-2, a 409 amino acid ~45 kDa scaffold protein and member of the arrestin family, highly expressed in the central nervous system. Beta-arrestin-2 plays a role in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling, through receptor desensitization and internalization. Beta-arrestin-2 may function in the regulation of synaptic receptors, and in scaffold-linking GPCRs to JNK3, thereby enhancing the GPCR-mediated activation of JNK3, associated with cell apoptosis.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human beta Arrestin-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.