|Application ||WB, IHC-P, IF, E|
|Calculated MW||41253 Da|
|Purification||Antiserum to human NOXO1was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Recombinant Human NOXO1.|
|Shelf Life||18 months from date of despatch.|
|Other Names||NADPH oxidase organizer 1, NADPH oxidase regulatory protein, Nox organizer 1, Nox-organizing protein 1, SH3 and PX domain-containing protein 5, NOXO1, P41NOX, SH3PXD5|
|Target/Specificity||Rabbit anti-Human NOXO1 antibody recognizes human NADPH oxidase organizer 1, also known as NOXO1, NADPH oxidase regulatory protein, Nox organizer 1, Nox-organizing protein 1 or SH3 and PX domain-containing protein 5. NOXO1 is a 376 amino acid ~48 kDa cell membrane associated protein involved in the superoxide-generating activity of NOX1 and NOX3 and is required for the development of crystalline gravity sensing structures of the inner ear (Lundberget al.2015).Multiple isoforms of human NOXO1 generated by alternative splicing have been described. Rabbit anti-Human NOXO1 antibody recognizes an epitope within the sequence “SGPQFCASRAYES” representing amino acids 238-252 of isoform 1 of human NOXO1, this sequence is common to all described isoforms of human NOXO1 (UniProt : Q8NFA2).|
|Preservative & Stabilisers||0.01% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human NOXO1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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