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Anti-Human PTBP1 (N-Terminal) Antibody

Goat Anti-Human Polyclonal Antibody

  • WB - Anti-Human PTBP1 (N-Terminal) Antibody  ABD11210
    Jurkat cell lysate probed with Goat anti human PTBP1 N-Terminal
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P26599
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 57221 Da
Additional Information
Purification Antiserum to human PTBP1 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide sequence DGIVPDIAVGTKR-C from the N-Terminal region of PTBP1 (NP_002810.1; NP_114367.1; NP_114368.1; NP_787041.1).
Shelf Life 18 months from date of despatch.
Gene ID 5725
Other Names Polypyrimidine tract-binding protein 1, PTB, 57 kDa RNA-binding protein PPTB-1, Heterogeneous nuclear ribonucleoprotein I, hnRNP I, PTBP1, PTB
Target/Specificity Goat anti-Human PTBP1 antibody; recognizes an epitope within the N-terminal (NT) region of human PTBP1, otherwise known as polypyrimidine tract-binding protein 1. PTPB1 is a multi-functional, ubiquitously expressed heterogeneous nuclear ribonucleoprotein (hnRNP), implicated in pre-mRNA processing, mRNA metabolism and transport. PTPB1 contains 4 RRMmotifs.PTBP1 is highly over-expressed in glioma and, along with its brain-specific homologue PTBP2, acts as a regulator of neural precursor cell differentiation (Zhanget al.2013). There are 3 described isoforms of PTPB1 derived by alternative splicing, isoforms differ in having insertions between the RRM domains 2 and 3. Goat anti-Human PTBP1 antibody is expected to recognize all isoforms of PTPB1.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human PTBP1 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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Cat# ABD11210
(40 western blots)
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