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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   Anti-Human FHL1 Antibody    

Anti-Human FHL1 Antibody

Goat Anti-Human Polyclonal Antibody

  • IHC - Anti-Human FHL1 Antibody  ABD11211
    Paraffin embedded human testis stained with Goat anti human FHL1
  • WB - Anti-Human FHL1 Antibody  ABD11211
    Human muscle lysate probed with Goat anti human FHL1
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13642
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 36263 Da
Additional Information
Other Species Dog,M
Purification Antiserum to human FHL1 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide sequence CNKRFVFHNEQVY from the internal region of FHL1 (NP_001440.1; NP_001153171.1).
Shelf Life 18 months from date of despatch.
Gene ID 2273
Other Names Four and a half LIM domains protein 1, FHL-1, Skeletal muscle LIM-protein 1, SLIM, SLIM-1, FHL1, SLIM1
Target/Specificity Goat anti-Human FHL1 antibody recognizes human Four and a half LIM domains protein 1, also known as FHL1, Skeletal muscle LIM-protein 1 or SLIM-1. FHL1 is a 323 amino acid ~30 kDa cytoplasmic protein containing multiple LIM domains. FHL1 is abundantly expressed by skeletal muscle and has been linked with several muscular dystrophy-like muscle disorders, including Scapuloperoneal syndrome (Quinziiet al.2008), X-linked severe early-onset reducing body myopathy (Schlesslet al.2011), and X-linked myopathy with postural muscle atrophy (Windpassingeret al.2008).Goat anti-Human FHL1 antibody is expected to recognise FHL1 isoform 5 and isoform 2, the latter being implicated as a negative regulator of RBP J- mediated transcription (Lianget al.2008).
Preservative & Stabilisers 0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human FHL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Emmanuele, V. et al. (2014) Fhl1 W122S causes loss of protein function and late-onset mild myopathy.
Hum Mol Genet. pii: ddu490. 2. Can, T. et al. (2014) Proteomic analysis of laser capture microscopy purified myotendinous junction regions from muscle sections.
Proteome Sci. 12: 25.

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Cat# ABD11211
(40 western blots)
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