|Application ||WB, IHC-P, E|
|Calculated MW||22588 Da|
|Purification||Antiserum to human LCN2 was raised by repeated immunisation of with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide sequence C-AILREDKDPQKMY from the internal region of LCN2 (NP_005555.2).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Neutrophil gelatinase-associated lipocalin, NGAL, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3, Siderocalin LCN2, p25, LCN2, HNL, NGAL|
|Target/Specificity||ABD11226 specifically recognises human Lipocalin-2 (LCN2), otherwise known as Neutrophil gelatinase-associated lipocalin (NGAL), a secreted glycoprotein and member of the Lipocalin family, which is highly expressed in the bone marrow, lungs, stomach, liver and adipose tissue, and is implicated in innate immunity and apoptosis.LCN2 acts as a protein transporter, through the binding of small lipophilic substances in the hydrophobic core. Expression of LCN2 is up-regulated during inflammation, and plays an important role in the innate immune response, by binding to bacterial iron-containing siderophores, limiting bacterial growth.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Lipocalin 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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