|Application ||WB, IP|
|Other Accession||Q6AZ50, Q9NT62|
|Calculated MW||35796 Da|
|Purification||Antiserum to human ATG3 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||KLH conjugated synthetic peptide corresponding to amino acids 17-32 of human ATG3. The corresponding sequence is identical in rat and mouse.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Ubiquitin-like-conjugating enzyme ATG3, 6.3.2.-, Autophagy-related protein 3, APG3-like, Atg3, Apg3l|
|Target/Specificity||Mouse anti-Human ATG3 antibody recognises ATG3 (Autophagy-related protein 3), otherwise known as APG3, a widely expressed E2-like enzyme, and member of the ATG3 family, which plays a key role in autophagosome formation, by catalyzing the conjugation of ATG8-like proteins to phosphatidylethanolamine (PE), in conjunction with ATG7. ATG3 also plays a role in the regulation of mitochondrial homeostasis and cell death, through conjugation with ATG12 at Lys243. Mouse anti-Human ATG3 antibody (ABD11248) has been shown to be suitable for use in immunoprecipitation using rat NRK cell lysates.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-ATG3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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