|Calculated MW||52497 Da|
|Purification||Antiserum to human ATG4C was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||KLH conjugated synthetic peptide corresponding to amino acids 51-65 of human ATG4C.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Cysteine protease ATG4C, 3.4.22.-, AUT-like 3 cysteine endopeptidase, Autophagin-3, Autophagy-related cysteine endopeptidase 3, Autophagy-related protein 4 homolog C, ATG4C, APG4C, AUTL1, AUTL3|
|Target/Specificity||Mouse anti-Human ATG4C antibody recognises ATG4C (Autophagy-related protein 4 homolog C), otherwise known as APG4C/Cysteine protease ATG4C, a cytosolic cysteine protease and member of the peptidase C54 family, predominantly expressed in heart, liver, skeletal muscle and testis. Orthologues of ATG4, play a central role in the cleavage of the C-Terminal region of the target proteins GABARAPL2, MAP1LC3 or GABARAP during autophagy, and studies have implicated that ATG4C may be particularly relevant to the autophagic response under stressful conditions, such as during prolonged starvation.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human ATG4C Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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