|Application ||WB, IP|
|Calculated MW||132821 Da|
|Purification||Antiserum to human CCAR1 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to an epitope within amino acid residues 700-750 of human CCAR1(NP_060707.2).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Cell division cycle and apoptosis regulator protein 1, Cell cycle and apoptosis regulatory protein 1, CARP-1, Death inducer with SAP domain, CCAR1, CARP1, DIS|
|Target/Specificity||Rabbit anti-Human CCAR1 antibody recognises human CCAR1 (Cell cycle and apoptosis regulatory protein 1), a perinuclear phosphoprotein expressed by several epithelial cancer cell lines, which has been implicated as a regulator of transcription, through association with components of the Mediator and p160 coactivator complexes, and its role as a p53 coactivator. CCAR1 acts as an inducer of apoptosis signalling, under the regulation of the epidermal growth factor receptor (EGFR), caspase-9 activation, the mitogen-activated protein kinase pathway, and in response to chemotherapeutic agents, and has been shown to act as a suppressor of human breast cancer growth.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CCAR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.