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Anti-Human AMPK alpha 2 Antibody

Goat Anti-Human Polyclonal Antibody

  • WB - Anti-Human AMPK alpha 2 Antibody  ABD11265
    Human liver cell lysate probed with Goat anti Human AMPK Alpha 2
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P54646
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 62320 Da
Additional Information
Other Species Dog,B,M,Rat
Purification Antiserum to human AMPK alpha 2 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Synthetic peptide sequence CPLDALNTTKP from the internal region of AMPK alpha 2 (NP_006243.2).
Shelf Life 18 months from date of despatch.
Gene ID 5563
Other Names 5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK subunit alpha-2,, Acetyl-CoA carboxylase kinase, ACACA kinase,, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase,, PRKAA2, AMPK, AMPK2
Target/Specificity ABD11265 specifically recognises AMPK alpha 2, otherwise known as PRKAA2, a Serine/threonine-protein kinase and the catalytic subunit of the AMP-activated protein kinase (AMPK), a central metabolic sensor, essential for the regulation of fatty acid and cholesterol synthesis, in response to fluctuations in nutrient and intracellular energy levels.AMPK has been implicated as a suppressor of cell proliferation of both normal and malignant cells, and recent studies have shown that the binding of AMPK to the PS domain of ULK1, is essential for ULK1-mediated autophagy, and that the phosphorylation of raptor by AMPK, plays an important role in autophagy induction.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human AMPK alpha 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11265
(40 western blots)
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