|Application ||WB, E|
|Calculated MW||62320 Da|
|Purification||Antiserum to human AMPK alpha 2 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide sequence CPLDALNTTKP from the internal region of AMPK alpha 2 (NP_006243.2).|
|Shelf Life||18 months from date of despatch.|
|Other Names||5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK subunit alpha-2, 188.8.131.52, Acetyl-CoA carboxylase kinase, ACACA kinase, 184.108.40.206, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, 220.127.116.11, PRKAA2, AMPK, AMPK2|
|Target/Specificity||ABD11265 specifically recognises AMPK alpha 2, otherwise known as PRKAA2, a Serine/threonine-protein kinase and the catalytic subunit of the AMP-activated protein kinase (AMPK), a central metabolic sensor, essential for the regulation of fatty acid and cholesterol synthesis, in response to fluctuations in nutrient and intracellular energy levels.AMPK has been implicated as a suppressor of cell proliferation of both normal and malignant cells, and recent studies have shown that the binding of AMPK to the PS domain of ULK1, is essential for ULK1-mediated autophagy, and that the phosphorylation of raptor by AMPK, plays an important role in autophagy induction.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human AMPK alpha 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.
Request Quote Here